ABSTRACT
O presente registro acerca da identificação de infecção aguda de dois plasmódios e um Trypanosoma constitui evento raro. Pré-escolar, sexo feminino, 5 anos de idade, apresentou síndrome febril; foi submetida a exame de gota espessa no qual foram identificadas formas assexuadas e sexuadas de Plasmodium vivax e P. falciparum, respectivamente, além de tripomastigotas sanguíneos de Trypanosoma cruzi. No peridomicílio, foram encontrados insetos da espécie Rhodnius sp. Os autores reforçam a importância dos estudos dos ciclos peridomiciliares de T. cruzi em ambientes silvestres na Amazônia e discutem a importância da estratégia de vigilância continuada de Trypanosomas spp. nos exames de gota espessa.
This report describes a rare case of acute infection caused by two Plasmodia and one Trypanosoma. 5 year-old female patient attending kindergarten presented persistent fever syndrome. She was submitted to thick smear exam, in which asexual and sexual forms of Plasmodium vivax and P. falciparum were detected, respectively, as well as trypomastigotes of Trypanosoma cruzi. Rhodnius sp. triatomines were found in the vicinity. The authors reinforce the importance of investigating the domiciliary cycles of T. cruzi in the Amazon region. Moreover, we discuss the importance of continuous monitoring of Trypanosomas spp. in thick smear exams.
ABSTRACT
BACKGROUND: Transfusion of Human immunodeficiency virus (HIV) infected blood is probably the most effective means of transmission of this disease. Despite intense efforts and investment to ensure safety, transmission of HIV still remains a real possibility in the transfusion service due to the fact that routine laboratory tests in most Brazilian government blood banks rely on the detection of antibodies. This leaves an immunological window period of from 16 to 22 days, which could be minimized to approximately 9 to 11 days if nucleic acid amplification tests were employed in screening. OBJECTIVE: To analyze the profile of blood donors who seroconverted to HIV positive from 2008 to 2010 in the coordinating blood bank of the State of Pará in respect to gender, age, marital status and educational level. METHODS: HIV seroconversion cases of blood donors who donated on more than one occasion at the coordinating blood bank of the State of Pará were investigated. Records from 2008 and 2010 were analyzed in respect to gender, marital status, schooling and age. RESULTS: Among the 157,432 donations in this period, 45 HIV seroconversions were confirmed. Of these, 95.56 percent were men, of which 86.67 percent were single, 53.33 percent had completed high school and 40 percent were between 23 and 29 years old. CONCLUSIONS: In order to improve the quality of blood and reduce the residual risk of HIV transmission in blood banks, it is necessary to know the profiles of donors who most frequently seroconvert and use nucleic acid amplification tests as routine screening.
Subject(s)
Humans , Male , Female , Young Adult , Blood Donors , HIV , HIV Seropositivity , Risk FactorsABSTRACT
Objetivo: discutir as recentes contribuições encontradas na literatura para o campo do diagnósticodas SMD. Método: pesquisa da literatura sobre o tema, destacando as principais ferramentasdiagnósticas disponíveis na atualidade e sua aplicação no diagnóstico complementar e de exclusãodas SMD. Considerações finais: nos últimos anos, tem havido um melhor conhecimento daetiopatogenia e características clínicas das SMD. Em virtude disso, o diagnóstico se tornou maispreciso, o que pode ter ocasionado um aumento no registro dessas desordens e não um real aumentoda incidência.
Objectives: to discuss the recent contributions found in the literature for the area on diagnosis ofthe MDS. Method: literature screening on the subject, detaching the main available diagnostictools in the present time and its application in the complementary diagnosis and of the MDSexclusion. Final considerations: currently, the knowledge on the ethiopatogeny and clinicalcharacteristics of the MDS has improved. In virtue of this, the diagnosis has become more accurate,what may have a caused an increase in the register of these disorders and not real increase of theincidence.